When Myron The Mildly Irritating first appears, the Titans assume he is there to take over the world, just as his brother would. Myron explains that he is not there to conquer the world, but rather to visit his favorite niece. When they learn he truly has no evil intentions, they welcome him into their home. As his title would imply, he is mildly irritating, but irritating enough to quickly get on the Titans' nerves. The Titans become fed up with his behavior, so the Mystery Incorporated (who had just helped the Titans solve a mystery) offered to teach him manners. Everyone's attempt to teach Myron manners fail, so the Titans decide to kick him out.
In their attempts to get rid of him, Velma discovers that Myron is a crooked real estate developer from the Netherworld. His real reason for being there was to annoy people into moving into the Netherworld, allowing him to make money. After uncovering his nefarious plot, the Titans threaten to take him down. Myron leaves willingly, claiming that they are all far more annoying than he ever was. With that, he travels to the fifth dimmension, hoping to have better luck there.
- Unlike his brother Trigon, Myron has no intention of taking over the earth. He would rather trick people into moving into the Netherworld and overcharge them.
- Apparently, there are many other creatures of the same species as Trigon and Myron.